It shouldn't matter. If the entire speaker is rated for 250w rms don't drive it at program with more than that. Find the sensitivities, then head over to crown audios amplifier power needs calculator and enter the distance from the speaker and the desired spl. Keep in mind a speaker that is rated 250w rms can handle brief peaks of three times program, which is 750w. Don't try an get more spl out of the speaker than the power rating is for and it won't blow. Additionally, be sure your amp has enough headroom to prevent clipping, clipped signals travel straight to the tweeter as DC, and most definitely will blow your tweeter.
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