Soooo, we CAN detect subtle differences in amplifiers... solid state, tube, digital, semi-digital designs make a difference. I'll agree, somewhat.
Digital cabling (I'll reach and point out synchronous/asynchronous in the category) makes less of a difference. I'll note how really well trained your ears need to be.
Room characteristics matter (#roommatters !) your room needs to have some "padding" to aid it in overcoming modes, inconsistencies, and what not.
Analogue cabling? Well, there is that 1 million dollar challenge, Golden Ears.
I've missed plenty, but just these simple factors alone, well I laugh at those that choose to imagine reality. Analogy: Let me not workout, but get plastic surgery while I still smoke, and then put on tons of makeup. Fake it till I make it!