So if I follow, there is nothing to be gained by running them stereo and the potential for something to be lost, correct?
I'm not absolutely sure that there is nothing to be gained from stereo subs. I do recall an interesting video over at AVS that featured commentary from an experienced installer, who didn't seem to be the black hat type, having a preference for front located, stereo subs. I think his take was that bass transient information is more important than absolutely smooth response, and he wanted the kick drums to sound (or perhaps feel) like they coincided with the rest of the band. I'm not sure if he was out to lunch or really on to something. And his explanation was a bit more fleshed out than my shoddy recollection of it.
Also, if your mains are weak in the mid-bass, co-located subs can be crossed higher to augment them without directional cues being an issue. Yes, that
may compromise bass smoothness, but you would essentially have full range, much harder hitting mains to play with.
The best route to take, since each and every listening room is it's own bag of acoustical quirkiness, is to test it out in situ, assess, tweak, assess, tweak...