harmony one, here also. There might be better units out there but this remote does every thing I have asked it to do. I also do not have to have someone come to my house and program it for me. Not sure if the crestron requires that?
Another Harmony One recommendation here. I've had one since the day Amazon started carrying it. The One replaced a Harmony...676 or something like that, the one with a plasti-chrome ring for the directional buttons and three colored faceplates. The One is vastly better. The button layout is so much more intuitive that despite using the other one for quite a while, after less than a day I was more comfortable with the One. The hardware feels nicer in the hand. And the charger/cradle gives one an instinctive place to put it, minimizing the risk of it ending up under couch cushions.
In the intervening years I've found no reason to replace it. It's easy to program from my Mac. Going from controlling a Denon receiver and including it in all activities to controlling an Anthem receiver and including it in all activities was a ten-minute process. Maybe.
Perhaps the biggest endorsement of the One is that, after using mine, both my mother and my sister's in-laws ended up buying them.
As for Android tablet as remote...I wouldn't be inclined to go that way. First, I like hard buttons on a remote. (That also excludes the touchscreen Harmony, mind.) I don't want to have to look at it to use it. Others may have different preferences, of course.
Second...I suffered through an HTC Evo 4G until Sprint finally got a phone that married reliable hardware and competent software*, and am very glad to have that experience behind me. No reason to repeat.
*Apple iPhone 4S, obviously. Previously they had a phone with (very) competent software in the Palm Pre, but the hardware was...not. As for durability, I'm not impressed with HTC or Samsung, either. Anyone want to see the result of an 8-pound cat stepping on my sister's Evo?