I was using a Denon 3805 for quite some time and then tried out a Rotel 1077 (the 7 channel digital amp). I used the 3805 as a preamp. I did notice a "different" sound compared to the Denon. The most concrete difference that I can say was that using the 3805's internal amp caused listening fatigue at higher listening levels. I didn't want to turn it up to much because I didn't enjoy the sound at higher volumes. I enjoyed the Rotel a lot at higher volumes, no fatigue. Then I tried out a Bryston 9BSST and noticed a change in the sound as well, I liked the Highs of the Bryston a lot more then the Rotel but the Rotel had very impressive low end. I preferred the Bryston sound to the Rotel, so stuck with the bryston. A few months later I upgraded the Denon 3805 to a Bryston SP1.7 and noticed a small improvement in sound, about 5-10% i'd say, whereas the Amp seemed to give more like a 30-40% improvement in sound. I've read a lot about how amps shouldn't sound different, ect.... from my experience, I perceived them to sound different. My Wife also agreed with my observations on the better sound from the external amp, but couldn't really hear a difference upgrading to the Bryston Pre\Pro. It's very hard to do a A/B test, takes to long to switch all the equipment to remember exactly how it sounds, But If I were to recommend separates vs. receiver, i'd say go with a good receiver, Yamaha or Denon, and then if you get the upgrade bug, try out a few external amps later on down the road that have a good return policy, so you can decide if you like the sound better yourself. I think the yamaha or denon make great pre\pros for their price point, vs units like the Bryston.
Brian