Depends on two things:
1) How loud are your listening habbits? If you like it very loud you will most likely encounter issues.
2) How large is your listening area/room? A large room combined with high volume with the M80's requires "big" amp sections.
Guys and gals, some 4 ohm speakers are much easier to drive than others. For some reason (Axiom has never really said why) the M80's require large amounts of power at high volumes. I suspect they dip well below 4ohms when driven hard being the primary reason.
And yes, I actually own m80's and an MPS1 and have seen it shut down front L/R channels on occasion when driven hard but not to insane or ear bleeding levels.
If you run into shutdown issues, the new Emotiva XPA2 amp should do the trick or if its an issue you don't like, send the M80's back and if you like the sound which i suspect you will, get the m60's instead which are 8ohm and much easier to drive hard.
Enjoy!