Ok, i see. I thought you wanted to run two separate amps at the same time when I read the title.
Someone else with more experience can chime here, but I don't see why not as long as both aren't sending power to the speakers at the same time.
That being said, if you use the same receiver both both HT and audio how would you stop the receiver from sending power to the speakers (since they are still connected to it) when listening to audio powered by the tube amp?