That Behringer iNuke amp is overkill for the Klipsh 280's.
However, should you be interested in a pro audio 2 channel amp for your front left & right speakers, I would recommend the QSC DCA1222 unit. It is from QSC's Digital Cinema Series products used in many theaters in US and Canada. This one has a power rating of a clean 200 watts/ch at 8 ohms. Of course, it could also bring your Klipsh's to ear-bleeding levels should you drive them hard. On the other hand, for normal listening levels, it would give you a clean, neutral sound that would allow the 280's to perform at their best, without much risk of damaging them:
https://www.qsc.com/cinema/products/power-amplifiers/dca-series/dca-1222/
That cinema amplifier has excellent specs and you won't be able to kill it. Actually, I am using two such amps on my HT system for actively bi-amping the front left & right channels, and I have excellent results. I will purchase the 3rd one for the center channel this fall. Several months ago, I started a thread on this amp and I will complete it with my global impressions, when I have received the third amp and used it for a little while.
This product is not sold in Pro Gear stores but is available through a QSC distributor. However, on the web I found two California based stores that offer it for $730, which is 20% off retail price. By the way, the inboard fans are rather quiet; I am sitting 6 feet away from mines and I don't hear them.
To conclude, this amplifier represents an option for a dependable 2 channel amplifier to drive the main speakers in a high quality HT system.