I'd say in general any of these room eq programs do better with more information about your listening area, so multi is better. The resultant sub level may not be your preference (it may be more a flat response), no problem in ticking it up a few dB for preference, many do. Some of the YPAO versions don't do much for the lower sub frequencies, either.
How did you place your subs? That can influence their response more so than the room eq....