Perhaps I should have been more specific... You can use about any 2 conductors of wire to get a line level signal from point a to point b. The issue is that because it is line level you are much more likely to get interference and hiss on the line when using regular speaker wire. Generally coax is used because the shielding on it helps to keep the line level signal clean from your A/V receiver to the subwoofer. There is also shielded wire that will work also.
When we have run into this before and have noticed noise on the line, we have used a couple of pieces from Sonance that lift the audio signal to a very low speaker level, then bring them back to line level. The added power helps to negate interference on the wire.