I would think so. As precaution, always turn it on first, let it warm up and then turn on the power amp. When done, turn off the power amp first, wait for a minute and then turn the headphone amp/preamp off. That should avoid popping the speakers.
Well I very wisely chose to use a "test" set of speakers when initially connecting the amplifier and testing it.
I have a Teac A-1D integrated amplifier with preouts, however when I turn it on and off it does pop (not through the internal amp, just the preouts) which I find aggravating. So I decided to try using the little Teac CR-H220's headphone output instead, no popping at all. I adjusted the level inputs on the Niles to account for the aggressive level control and some hiss. Voila, it sounds great. As a bonus the amplifier has loop output so I connected my subwoofer there.
It's hilarious how far apart in quality the CR-H220 and A-1D appear to be. By looking at them one would think the A-1D to be superior, but most frustrating, it isn't.