Them Klipsch speakers never sound rite to me, super sensitive, and they don't need much power, unless your dog chewed your cables up that is not an issue, try stretching a piece of paper towel over the tweeter, maybe that will help, if its a step in the rite direction you are just hearing what the klipsch tend to sound like.. BRIGHT, aggressive, and fatiguing.., Some people love them, they kill me since I am sensitive to bright highs...
I would send the amp in for a checkup if it has never been, or ask some of the guys here how to check it all out your self, keep in mind that guy is 35+ years old who knows how many songs she has pumped out by now... But I honestly don't think its an issue with your wire or amp, I think you get a warmer pair of speakers in that room or treat the room if its is a problematic setup and you will get better sound... sometimes its easy, curtains, throw rugs, placement moves, ect...