In your situation, I would go the DIY route. Taking 1" off of all those dimensions, to ensure the unit would fit, and figuring .75" mdf for the enclosure you are left with 3.79 ft^3 per location to work with. You could easily do a pair of high quality 12" subwoofers in low tuned (20hz and down)ported enclosures with that type of volume available. Not to mention it would probably be cheaper. A pair of JL Audio 12W7 subs ($1300.00 street price), a Behringer EP 2500 (run one on each channel for $349.99), and a Behringer DCX2496 ($269.99) and you will have a world class sub system capable of knocking your socks off in that room for just over $1,900.00 I am also figuring high on the "street price" of those subs.
You could also go the sealed route if you are doing the Behringer EQ/Crossover but you would have a bit less SPL. Sealed would still be quite plenty in that room with those woofers.