Two channel source to 7.1
Yes, there are several ways to get a two channel stereo source to play on all speakers.
The first way is a 7-channel stereo mode with outputs the same information to all channels.
The second is DSP modes like Dolby PrologicII/x and DTS NEO:6. These take the 2 channel sound and output different information over different speakers for a surround sound like experience.
Most receivers will also output LFE to the subwoofer for 2.1 listening unless they are in a "Pure Direct" mode which bypasses all digital processing.
So look for a receiver will the above features. They are pretty standard on most new models.