Electone,
While I am generally not a huge fan of in-ceiling surrounds, I have been faced with several rooms recently where there were no other alternatives. In many of those cases, I have had the most success with treating at least the top 50% of the rear wall of the room with acoustical diffusors. The tweeters of the in-ceilings were then aimed (aimable tweeters is definitely a prerequisite here) at the center of the treatment area on each side, angled slightly towards the physical center of the wall. (I have only done this in 5.1 applications, but a similar approach should work for x.1 systems.) The effect of this in one recent installation was to successfully create the illusion of lateral surround, even though the source was in the ceiling.
Thus, I would ask you if you have any treatment on the rear wall? If not, you might consider installing some diffusors and aiming your in-ceilings as described above.
I will offer up an additional opinion: This generally does not sound as good, in terms of an enveloping surround field, as when you can us in-wall, on-wall, or otherwise in-room surrounds and place the seating area a decent distance away from them. I have typically found that having no seat closer than about 3'-4' from any surround loudspeaker tends to yield the best results in a properly treated room.