Yes thats possible.
The only issue is the analog outputs of computers are fairly noisey (hissing sound). It's one of the reasons the logitech 5.1 sets has a hissy center.
Plus, you would have to keep room and a computer running.
One thing to note is that those speakers are designed for Nearfield listening. SO if a large room, they might loose output, imaging, soundstage etc.
SheepStar