JC is right. I would also add the following
There is the best way and then there is good enough, and then there is "Oh my God I hope this works and doesn't suck" I am going to add "The Best Way"
You said that the room was already finished. No biggy if you do not mind a little mess/touch up. Having said all that I say to the following:
1. Take card board and cut out squares to represent the TV, Center Chan, and R/L speakers. Then Hang them on the walls were you would "Like"The system to go.
2. Take a stud finder and now mark were the 2x4 or 2x6 studs are. This will let you know if you were going to have an in wall speaker right in the middle of the stud.
3. Once you find were your studs are move the cardboard for the speakers in between the studs. Do not worry about the TV yet. Just the 3 speakers. (You did say in wall speakers right?? Cause if you are using in wall speakers they come with a cardboard cut out. Use that cause it is the right size)
4. Trace the card board with a pen or something and remove them. (Include the TV)
5. Cut the sheet rock out for the speakers.
6. For the TV cut out a hole in the dead center 6 inch high, by crap...trying to remember he length of the Peerless mounts.......well do about 10 or so inches on either side.
7. Add support for your mount. either with 2x4's or 2x10's something to give you a WIDE area and lots of strenght to hang your plasma mount on.
8. You also have huge holes for you to fish your power and speaker wires through. You mentioned crawl space so you can drill straight down through the base place and get to the crawl space.
9. Check under the crawl space before drilling! You might hit a pipe, electrical wires just make sure that you will not hit some thing before you drill.
10. Like JC Panny said, put your power on one side of the 2x4 stud and the other stuff on the other side.
11. after wire has been ran for everything, install your speakers.
12. Patch hole in sheet rock were plasma is going. Paint.
13. Hang mount on new support area.
Set everything up and enjoy.
There are a few things that I did not mention, but assumed that they were obvious things so I did not. As well as this post is already taking to long...
Hope that helps.