I had a weird problem with cable arrangement one time in 35 years of playing with this stuff, and that was when my old Audio Pulse Time Delay started picking up some weird motorboat noise suddenly, and putting it into the rear surrounds. It was right after I had moved everything to another room and it drove me crazy. After a drawn out process, I finally figured out it was my CD player causing it, only when NOT playing anything, it only did it when sitting there with the power on. After I replaced the attached cable on the player, with a longer, better one, and put a whole bunch, like 7 or 8 Ferrite chokes on the cable, was I able to get rid of it.
Other than that, the cables are just bunched up and never had any problems.