Well speakers are always the most difficult choice. I assume that you have had a chance to audition the Spendors. If that is so, then I assume you feel you would be happy with them long term. Speakers are actually the first thing to pick out. If you like them I'm not going to second guess your choice. Spendor is one of those great companies founded by engineers that were part of extensive speaker research done at the BBC. So those speakers have a good pedigree.
As I have said, I feel strongly now that when putting together a new system, there are pressing reasons to have the audio and video joined at the hip so to speak.
Now you seem to have picked out a 4K TV. I assume as with the speakers that you are happy with the screen you chose.
Now as with audio before, the chain is best with peripherals to preamp to TV and power amp to speakers. Or the preamp and power amp can be in the same box in which case you have a receiver. The higher end receivers also have pre out outputs from the preamp stage so that you can use external amplification. Really what is best is to have the audio and video processing done in the same unit.
Now those speakers you have picked out will be an easy drive, so I don't think you would absolutely need external amplification to start with.
So I think this unit would fit the bill for you.
I think from a cost effective point of view a receiver will do what you want. That will be the simplest solution and easiest to use.
That unit has preouts, so if you feel the need for higher quality power amplification that it is very easy to incorporate. If you feel the need for clearer and focused dialog then it is easy to add a center channel.
Now the audio quality in the preamp and processor stage will be at least as good as the Rega units you picked out, and the power amps almost certainly better.
Now the computer I'm not certain as to your needs. You have picked out a laptop as I suppose you want to use it on the move. However the best Dell units are there Latitude series.
In my view it is not optimal to mix work and pleasure when it comes to PCs. For AV systems I recommend and use PCs built round the integrated Intel Ivybridge i5 processor. Again this keeps audio and video bound at the hip. You don't need a screen as your TV is the screen and your PC connects to the receiver via HDMI.
The
Intel NUC i5 has a lot to recommend it. You have to add what RAM and SSD you want and buy Windows 10.
With Oppo gear becoming unavailable Cambridge Audio have a similar unit.
Now with modern media that can have significant lower bass content then a sub is something you should consider. I would look at the SVS, HSU and Rhythmic sites for a start. Your receiver has bass management so integrating a sub should be no problem.
So I have done my best to rough out a system that should be straight forward to use and be capable of expansion, especially in terms of being able to input a wide range of peripherals like an over air DVR or other streaming devices. However a unit like that NUC will basically allow you to pull in pretty much any stream out there.
Although this system might seem complex, it will actually in practice be much simpler in day to day use. Especially it will keep AV bound and you should not run into latency issues between audio and video.
If you want to completely separate the pre and power sections then you would need and AV preamp and and external power amp. This is the highest road, but in view of your speaker choice using and AV receiver will be more cost effective and simpler to set up. In addition when all is said and done you want to maximize both your audio and video experience, especially considering your investment in both.
I'm leaving for the airport early tomorrow as my wife and I are embarking on a two week tour of the Canadian Maritime Provinces which we are really looking forward to. So I will not be in touch until we get to Halifax NS tomorrow evening.
Good luck.