Wow, So even one F15HP wouldn't me enough?
Outside of Rythmik, what else would you recommend?
That's hard to say. I have dual sealed 15" subwoofers, and while running one in my over 5000 cu. ft. area it was great for music but a little lacking for Home Theater. Adding the second one sealed the deal, and now I have much more headroom and a more enveloping experience. This isn't to say the same situation will apply to you, as your room and tastes are likely different.
I would call Rythmik since you're pretty keen on going with one of their products (great company, by the way); they'll know for sure if one sealed F15HP will be enough for that room size and your listening preferences.
Other great companies would be:
SVS, Epik, Outlaw, HSU, Elemental Designs, JL Audio, Funk Audio (Funkywaves) and Chase Home Theater.