I have the c272 and the 2200. Both are great amps. I use the 2200 for front channel in my NAD 763 home theatre setup as it has better dynamics than the c272, but still has a nice sound. While a very nice amp, smooth, powerful, etc... it muddies music a bit (poorer imaging, smaller soundstage, less transparent). The c272 sounds less veiled, cleaner at volume, but does not have the same kick in loud transients. Incidentally, the 763 is also nice, but I found the sound a bit harsh/bright with lots of hash at volume. I cannot not listen to U2 for example using the 763 to power the fronts as it is harsh and fatiguing. Swithcing to the 2200, it becomes warmer and very listenable with tons of kick. However, the instruments blur together. Going to the 272, the music take on depth and more detail without the bright/harsh characteristics of the 763.
If cost is an issue, go for the 2200 - you will be very happy with it. If cost is not an issue, go for the 272 as it brings out the texture a bit better.
Having said all of that - I have a 2200 if you want one... would like let it go for about $225ish.