Hi backatcha.
No, the mdf will not protect you from interference. Most speaker cabinets are mdf and offer no protection, either. How do you get such big drivers so close to the tv? Is the tv very low, or are the speakers on a stand/cabinet? You can get away with having the drivers two times the distance from the tv as their size...but I'd guess you're having a tad of disturbance on your video right now.
The flickering is your tv's way of telling you it likes its rock and roll more subdued, lol. If it's possible to do, I'd suggest you move the speakers a bit further away from the television.