Normally, the level controls are labeled with 0 being the standard, and then positive numbers for higher levels, and negative numbers for lower levels. Normally, it is best to adjust them as needed for proper channel balance. Them all being set high or low is not going to affect the power output capabilities of the amplifier, so there is no point in setting them all high or low.
Basically, they are all of them volume controls, and setting them low and then adjusting the main volume high is not going to help, and setting them all high and then adjusting the main volume lower is not going to help. This is assuming that the equipment is properly designed and properly functioning, of course. If the equipment is not properly designed, there could be issues with the noise floor or overdriving some stage of the amplifier, and to avoid those, it would be best to keep things near 0 or the standard point.