Regarding opting for the Bose system, your family member looking to set up the system needs to make a few decisions,
1) Is value for money important
2) Is audio and video quality important
3) Capabilities for current and future technologies (i.e. HDMI, Hi-def audio, video, etc.)
4) Sufficient inputs and outputs
5) Are aesthetics and ease of setup/ use more important compared to all points above
Bose gets high points for brand image, aesthetics and ease of setup/ use, but they pretty much missed the mark on everything else. The Lifestyle 38 is going for about $2700. In this price range there are several options to put together a stunning home audio setup, considerably better than the Lifestyle 38. It will take some time to do research during equipment selection and a little effort during setup.
Regarding opting for wireless speakers, IMHO, run cables.