Seth,
If you can tell us your budget, we can give you some better options.
Have you already bought the Onkyo? If not you may want to consider other options because the Onkyo AVR's have a reputation for overheating/failure. That may not be true of the 444 you are getting. I'm not sure if it is certain models or across the board.
As for the speakers, you can do much worse, but you can also do much better.
If you give us the following info, we'll come up with good options for you:
1) Budget and items you need to buy with that budget.
2) Percent music/HT (50% music/50% HT, for example).
3) How large is your room (give us length, width, and height).
4) How many speakers are you planning to use.
5) Would a center go under or over your screen (or behind if you are getting an acoustically transparent screen). Are their dimensional restrictions on the center? (for example only 7" between the bottom of the screen and the top of the console where the center will sit).
That should get the ball rolling.