Not easily. That connector has nothing in common with the 1/8" stereo mini jacks other systems use. 1'8" stereo mini plugs have three wires. This connector has nine connections, most likely:
1) 3 to replace that 1/8" stereo mini jack for it's input and
2) 4 outputs, 2 for each speaker and, most likely,
3) 2 more for some dort of volume control, which is most lilely on one of the two satellite speakers. that's just a guess.
Now, which is which is beyond me.
If you could figure out which three are item 1, that would be a start. I don'tthink you would need to worry about item 2, but I have no idea how item 3, if that's a reality at all, would have on the overall picture.
Oh, other "computer subs" are simply the central point for other 2.1 "integrated systems" just like this. They are NOT real subwoofers made to work in home systems. They are made for computers..