I find the cheeky humor interesting. It's been a pretty fun game so far and I think the depravity that is "possible" in the game is no more than a lot of 'fantasy' based RPGs that don't get this kind of attention.
Yes, it is an adult game. I wouldn't even play with my kid around. But it's fun and has a real wit that I can certainly relate to.
"...I got a Yoga bill like a M***********."
That line just made me laugh out loud. They make fun of the new age, celebrities and both sides of the political spectrum. It's certainly not a dumb game.
And.. oh yeah, it's a game too. Sometimes the in-game physics aren't the greatest. You bump into people too easily or fall off things. But overall they did a great job at making virtually everything in the game react to you in a somewhat realistic manner.
The sheer number of cutscenes makes it infinitely entertaining although just a little more linear than something like Oblivion. It's well acted and the dialogue is smart yet not too smart, it's realistic.