mbaylor,
There are computer programs that can assist you with layout and placement. I don't know if it's popular on this forum, but
CARA is quite useful, even if the learning curve isn't that great.
RPG's "Room Optimizer" will also do a good job, though, again, the learning curve is a bit steep. Both programs are priced below US$100.
There are also various thoughts ("rules of thumb") on placement of loudspeakers and listeners with respect to room mode distribution. One of those is given in a post above. Another is placing speakers to correspond to strong modal nulls - e.g., nx/4, where n is an odd integer and x is a room dimension. This tends to work best for full-range loudspeakers and subs. This suggestion is usually accompanied with placing listening seats at mx/3 and/or mx/5 (and/or, if the room is big enough, mx/7) locations, where m is an integer, to avoid any strong modal peaks or nulls. (If you do the math, this jives somewhat with the method above since 2/5 = 0.40, which is close to the 38% figure.)
Yet another suggestion would be to use the mx/3,5,7 method for loudspeakers
and listeners.
There are more suggestions that involve, for example, front channels being at least x/10 from the front wall (where x is the front-back distance); placing the listening position 0.7*width back from the front wall (e.g., if the room is 20 feet long and 15 feet wide, place the listening position at 0.7*15 = 10.5 feet back from the front wall); and so on.
It might be more important to remember that there are
definitely some placements to avoid completely. The center of the room (something the 0.7*w formula often comes close to, unfortunately) is to be avoided. Having a couch up against the back wall when the purpose is surround sound is also a big no-no.
Having adequate acoustical control in the room can also make exact placement much more of a non-issue.