D

Dude#1279435

Audioholic Ninja

In a startling revelation, a Washington Post analysis has found that more vaccinated people are now dying of the Covid disease and 58 per cent of coronavirus deaths in August in the US "were people who were vaccinated or boosted".

For the first time since the beginning of the pandemic in early 2020, a majority of Americans dying from Covid were at least partially vaccinated, according to the new analysis of federal and state data.

"In September 2021, vaccinated people made up just 23 per cent of coronavirus fatalities. In January and February this year, it was up to 42 per cent," the report mentioned.

The death among vaccinated people is increasing due to the waning efficacy of Covid vaccines and "increasingly contagious strains of the virus being spread to elderly and immunocompromised people" among those who have taken at least one vaccine dose.

"We can no longer say this is a pandemic of the unvaccinated," said Kaiser Family Foundation vice president Cynthia Cox, who conducted the analysis on behalf of the Washington Post.

Outgoing White House Chief Medical Adviser, Anthony Fauci has emphasised the safety and efficacy of the approved Covid vaccines in preventing severe illness and deaths, encouraging people to get vaccinated and boosted as soon as possible.

He said that coronavirus vaccine effectiveness wanes over time and the disease shouldn't be compared to other vaccine-treatable illnesses because of new emerging variants.

"My message, and my final message, maybe the final message I give you from this podium, is that please, for your own safety, for that of your family, get your updated Covid-19 shot as soon as you're eligible to protect yourself, your family and your community," Fauci said.

"I urge you to visit vaccine.gov to find a location where you can easily get an updated vaccine, and please do it as soon as possible."

Older people were always especially vulnerable and now make up a higher proportion of Covid fatalities than ever before in the pandemic, reports Scientific American.

Today in the US, about 335 people will die from Covid -- a disease for which there are highly effective vaccines, treatments and precautions, it added.

"Covid deaths among people age 65 and older more than doubled between April and July this year, rising by 125 per cent," according to the Kaiser Family Foundation.

The World Health Organization reported a nearly 90 per cent drop in recent Covid-19 deaths globally compared to nine months ago, but still urged vigilance against the pandemic as new variants continue to rise.

Overall, the WHO has reported 629 million cases and 6.5 million deaths linked to the pandemic.
In hindsight I think I should've asked how many vaccines have they had?
 
ryanosaur

ryanosaur

Audioholic Overlord
I got my Bivalent last Friday. Barely a side effect. Tiny little bit of soreness in my shoulder, unlike the previous shots that gave me the Mike Tyson KO jab to the shoulder.

Here's the thing about these vaccines... And I'm not saying this as a political statement:
Let's please consider what a real vaccines is capable of by looking at how Polio and other diseases were effectively wiped out by said vaccines.
That level of efficacy is clearly NOT apparent in the Covid vaccines. Where effectiveness of other Vaccines can be measured by a decade or more of protection, here with the current vaccines for Covid we are measuring their effective protection by months.

I am clearly not a Virologist and again, there is no political motivation behind my statement as a proud recipient now of four 'jabs' in my arm. Yet I do question if there is ever going to be a vaccine that will give us the level of protection against any Coronavirus or Flu which we apparently had from Polio Vaccines.
Is this a stopgap measure? Is there any idea if greater efficacy will ever be realized so that a single shot may last 5-10 years?
What is the long game for this looking like?
 
Swerd

Swerd

Audioholic Warlord
Let's please consider what a real vaccine is capable of by looking at how Polio and other diseases were effectively wiped out by said vaccines. That level of efficacy is clearly NOT apparent in the Covid vaccines. Where effectiveness of other Vaccines can be measured by a decade or more of protection, here with the current vaccines for Covid we are measuring their effective protection by months.
When I worked at the NCI, I tried to figure out why standard immunology methods failed to develop vaccines against cancers. I used to ask real immunologists the same questions as yours.

One of them answered that developing the highly successful vaccines against polio was a rare home run in vaccine development. It worked well right out of the gate, without requiring extensive development. Essentially, we were quite lucky with polio. It's like a young baseball player wondering if he should give up because he can't hit just like Ted Williams. Keep trying, and don't beat yourself up if you don't hit a home run on the first pitch. Measles vaccine is a similarly successful, but it took many years longer to develop the vaccine than for polio.

Developing vaccines against other viral diseases have been highly variable. We have fairly successful vaccines against polio, small pox, measles, mumps, rubella, chicken pox, human papiloma virus (HPV), to name a few – but where are the vaccines against HIV, Herpes, any of the common cold viruses, respiratory syncytial virus (RSV), and others?

In contrast to viral diseases, the vaccines developed against bacterial diseases (diptheria, whooping cough [pertussis], tetanus, etc.) have been much more successful. And then there are the numerous failed attempts at developing vaccines against a higher microorganism, malaria.

If we understood more about the immune system, we'd be hitting more home runs.
… I do question if there is ever going to be a vaccine that will give us the level of protection against any Coronavirus or Flu which we apparently had from Polio Vaccines. Is this a stopgap measure? Is there any idea if greater efficacy will ever be realized so that a single shot may last 5-10 years?
Ask me again 10 years from now.

It might be useful to read about the history of the development of some of the more successful vaccines. These efforts took years, decades, or longer. Only polio was a home run at the first swing.
https://en.wikipedia.org/wiki/Measles_vaccine

https://en.wikipedia.org/wiki/Polio_vaccine

https://en.wikipedia.org/wiki/Vaccine

 
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ryanosaur

ryanosaur

Audioholic Overlord
When I worked at the NCI, I tried to figure out why standard immunology methods failed to develop vaccines against cancers. I used to ask real immunologists the same questions as yours.

One of them answered that developing the highly successful vaccines against polio was a rare home run in vaccine development. It worked well right out of the gate, without requiring extensive development. Essentially, we were quite lucky with polio. Measles is a similar success story, but it took many years longer. It's like a young baseball player wondering if he should give up because he can't hit just like Ted Williams. Keep trying, and don't beat yourself up if you don't hit a home run on the first pitch.

Developing vaccines against other viral diseases have been highly variable. We have fairly successful vaccines against polio, small pox, measles, mumps, rubella, chicken pox, human papiloma virus (HPV), to name a few – but where are the vaccines against HIV, Herpes, any of the common cold viruses, respiratory syncytial virus (RSV), and others?

In contrast to viral diseases, the vaccines developed against bacterial diseases (diptheria, whooping cough [pertussis], tetanus, etc.) have been much more successful. And then there are the numerous failed attempts at developing vaccines against a higher microorganism, malaria.

If we understood more about the immune system, we'd be hitting more home runs.
Ask me again 10 years from now.

It might be useful to read about the history of the development of some of the more successful vaccines. These efforts took years, decades, or longer. Only polio was a home run at the first swing.
https://en.wikipedia.org/wiki/Measles_vaccine

https://en.wikipedia.org/wiki/Polio_vaccine

https://en.wikipedia.org/wiki/Vaccine

An interesting read about the potential of a new mRNA flu vaccine:
 
Swerd

Swerd

Audioholic Warlord
A universal vaccine against a wider variety of influenza virus sub-types has been a dream for a long time. In a previous post (#7,434 last January), I tried to explain how influenza virus manages to change it's coat each year, creating new immunologically distinct viruses each year. There are 18 known types of flu virus's hemagglutinin protein and 11 known types of neuraminidase protein, so, in theory, 198 different combinations of these virus-surface proteins are possible.

The present way to make new vaccines against these flu strains is slow. It takes at the least, 2-3 years of work to grow enough of the new strains in chicken eggs to have enough to make new vaccines. Because new flu virus strains appear each year, this has become a large scale, continuing effort. Even if we don't succeed at making a universal flu vaccine, that can generate immunity against most strains of flu, these new mRNA vaccine methods will be much faster at making each year's vaccines than the existing methods in hen eggs.
 
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