>>>SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses<<<\n\n[URL unfurl=true]https:\/\/www.nature.com\/articles\/s41541-021-00414-4[\/URL]\nIf this pans out it will be quite an amazing achievement.Thanks for the link to that NPJ Vaccines paper. The introduction and discussion sections are a good read.\n\nThe authors careful attention to the SARS-CoV-2-specific CD4+ and CD8+ T-cell responses generated by the vaccine are excellent. Those immune T-cell responses look like they're durable and adaptive. It took a lot of work to get all that good info.\n\nIt would be very interesting to try a combined vaccination scheme: the 1st dose would be this new SARS-CoV-2 ferritin nanoparticle vaccine, followed by a boost using one of the mRNA vaccines. Would that result in better or different (longer lasting) immunization than two doses of the ferritin nanoparticles, or two\/three doses of mRNA vaccines?