Hi FLMike,
I'm using a TX-NR801 as a digital signal processor in my system so I can only speak for the preamp section. I replaced a Sunfire Theater Grand II with this unit.
With my amp, the sound is clear, slightly warm and slightly forward. I'm very happy with the sound.
Setup is very straightforward and the menu options give a lot of user control. It's definately more flexable than my 4-year-old Sunfire.
The ability to play audio files on my computers is very nice and works quite well. I'm not as impressed with the internet radio.
The 801 is limited on the stations that can be received by the software being used. You can only access stations identified on the server Onkyo is using. Most are relatively low bandwidth.
Set at 6 ohms, the unit runs pretty hot. If you set it to 4 ohms, it will run much cooler. The only negatives to the unit are no PLIIx or composite/s-video upconversion.
The Perfect Vision had a review of the Integra DTR 7.4 (the Integra version of the TX-NR801) in their July/August issue.
They said "the DTR-7.4's overall sound came closer to that of a high-quality multichannel controller/amplifier (e.*., Parasound's fine C2/A52 combo) than it did to that of a typical mass-market AVR."
Onecall currently has this unit on sale for $749.00 new. Here's a link.
http://ww1.onecall.com/PID_20578.htm
If I can give you any other info, please let me know.