It doesn't look to me like tower surrounds are very workable in that room. My recommendation would be to use in-wall or in-ceiling surround and surround back speakers.
But if you want to keep what you have, you might try putting the towers on the back wall as the surround back channels with the bookshelf speakers on the walls to the right and left of the sofa facing the viewing position.
Or you could move the sofa closer to the screen to allow enough space to put the towers behind it, then move the bookshelf speakers to the back wall.
