@Winkleswizard
You make some good points, but let me clarify some things.
"While I agree minidsp is a great deal, it is likely to be a major investment in your time."
It will require a learning curve with REW, but it need not be a major investment of time.
"Moving the microphone slightly can reveal very different frequency responses. Measuring from many locations to equalize room response is a major investment in time and manually attempting to adjust is a very iterative process as there can be significant dependencies. More subwoofers and other speakers usually helps, but adds complexity."
The idea that's worked best for me is to give Audyseey/ YAPO etc the best to work with by using MiniDSP to eliminate major bumps and dips. That way any notch adjustments done post RC will not effect much in other seats; and generally it doesn't. However, I check them too, and they measure very well too. My suggestions with MiniDSP are subwoofer exclusive, and more subs is always a good thing, but for most rooms two subs strikes the best balance, all things considered, four is optimum, but not always possible for a variety of domesticated restrictions.
"Accurate location of each microphone position for every measurement cycle requires discipline. Am not saying there is no value, but is not for everyone."
This isn't hard.
"For comparable money, you are likely to get better return by adding some room treatment. In any case, you should get audible differences, but it is easier if you are trying to optimize one sweet spot vs. many."
I agree that room treatment has benefit for sound above 250 cycles, but not below. Applicable sound treatment for below 80hz costs much more, and takes up A LOT of space, and YMMV big time.
"Am familar with Audyssey, do you know if YPAO does anything special for multiple subwoofers?"
Not sure
"One final note, better can be subjective in home theater applications. Reducing standing waves should mean better sound, but if the listener likes the impact produced with them, reducing the standing waves may not be considered an "improvement". I have separate systems for music and home theater and tune them for the application."
How much we reduce them, and or how much we increase them more, and or other areas is deep deep down the road of preference. MiniDSP is the king of allowing one to curve response to their own preference. That said, I set my MiniDSP to my preference with movies (generally one standard), and since I use my Laptop via iTunes for music, I use the on-board graphic EQ to adjust to the many standards seen in music recording.