Lol, believe me that is a lot more work than any casual hobbyist would want to do. Yes, you can determine room gain like that though. That is what organizations with anechoic chambers do to get measurements below frequencies where the wavelengths are larger than the distance to room surfaces; they make compensation curves referenced to groundplane measurements. But what are the savings in going through with that for an average audio enthusiast? I would say it's a lot easier to get a very capable subwoofer that can handle any type of room. The price difference between a ported sub vs sealed sub when all other things are equal is not that great. Compare the prices of the ULS-15 mk2 to the VTF-3 mk5 or the SB-2000 to the PB-2000.
So if the question is what is the least expensive option that has a range of responses that can tackle different rooms, off the top of my head I can say the Hsu VTF-1 mk3, which is a bit over $400. But the truth is you can plug the port on any bass reflex subwoofer which will roll off the bass in the 40s or high 30s, and that might accomplish what you are after: eliminating too much boost through room gain below 30 Hz.
I think taming peaks in bass is probably Audyssey's only real value, aside from automatically setting the phase correctly between speakers and subs. I wouldn't use it to 'tune' subs exactly, and that could turn into a problem, like what might happen if audyssey tries to boost the low end of a sealed sub in a room that isn't getting any low-frequency gain; it becomes very easy to overdrive that sub. If there is way too much low end gain, as you know, Audyssey can only cut down on that so much as well. The usefulness of Audyssey in shaping the low end only goes so far, but it's certainly better than nothing.