I would go for the Klipsch between those two, especially since your room is large. The Klipsch measures extremely well. Then again, it is a lot more expensive, at least at MSRP. It is quite a bit more sensitive as well, measured at 92 dB by S&V. S&V also measured the Studio 65s, which were shown to have an 85 dB sensitivity. For the same juice, the Klipschs will get more than twice as loud as the Deftechs.